Crohn'sCanada
  Addressing the alarming rise of the bacterium "Mycobacterium avium Paratuberculosis"
 
in the environment and the growing evidence linking this bacterium to Crohn's
disease.
   
 
Founded: September 2001, updated March 15, 2013
 
                                                                                      

Founders: Diane and Michael Fagen

Contact Info: dianef84@yahoo.com

Home

Our Mission and our Goals

History of Crohn's Disease, Johne's disease, Mycobacterium avium Paratubercuosis

Recent Article Updates

Links to Articles
Page 2....3....4.....5

Perception of Risk

The Precautionary Principle

What is a Reportable Disease

Health of Animals Act, SC 1990, c 21

List of Reportable Diseases and REGULATIONS PRESCRIBING CERTAIN DISEASES AS REPORTABLE DISEASES

NRC National Science Library

Public Health Agency of Canada

Never In My Milk

Picure Gallery

Links

Messageboard

ree Republic/News Activism/Topics - Post Article

Research

La Presse,  April 8, 2001,  Never in My Milk? by Marie France Coutu

The Canadian Media


Canadian Medical and Government

Canadian Veterinary

Canadian Raw Milk Advocacy Group

 

Let's Talk



 

Taking Action

Link To Us

Does Mycobacterium Paratuberculosis cause Crohn's disease by Alan Kennedy  

(PARA) PARATUBERCULOSIS AWARENESS & RESEARCH ASS.,INC



Shafran's Gasterology Center

The Johne's Information Center

History of Early Research on Crohn's disease

Dr. B. Crohn

Got Milk? by Michael Greger, MD Updated January 2001

THE CROHN'S CONNECTION  by Lisa Chamberlain

Dire Warnings About Johne’s
Disease A wake-up call for the dairy industry?

Micobacteria and Crohn's Disease

Dr. Chiodini's Tables

American and European Links

University of Wisconsin School of Veterinary Medicine

Health Canada

Action Medical Research

 

University of Guelph

NACC

 

 

 

 

 

 

 

 

 

 

What Is Crohn's Disease?

WHAT IS MYCOBACTERIUM PARATUBERCULOSIS

Mycobacterium avium subsp. paratuberculosis: pathogen, pathogenesis and diagnosis E.J.B. Manning & M.T. Collins School of Veterinary Medicine, University of Wisconsin,

Mycobacterium Partuberculosis Linked to Multiple Scleroisis and Autism Update!!!!

Clinical Trials and Articles linking Multiple Sclerosis to Mycobacterium Paratuberculosis

 

We at MAP-Canada would like to dedicate this site to Dr. Thomas J. Borody of Australlia, Doctor Rod Chiodini (U.S.A.) and Doctor John Hermon-Taylor of the U.K., PROF THOMAS BORODY, the founder and Medical Director of CDD.(Center for Digestive Diseases. His keen interest in medical research led to the establishment of the Centre, so as to provide both diagnostic procedures and effective treatments, and to my husband Michael Fagen, who lost his 27 year battle against Crohn's disease on May 11th, 2003.

Dr. Rod Chiodini (Rhode Island Hospital and Brown University, Providence, RI, USA) and Prof. John Hermon- Taylor (St. George's Hospital Medical School, London, UK) are two of the most prominent proponents of an association between M. aratuberculosis and Crohn's disease. Indeed it was Chiodini and his co-workers ho, in 1984, successfully cultured the first two strains of M. paratuberculosis in the USA from patients with Crohn's disease. since then this organism has been sporadically cultured from humans with Crohn's disease and a total of 10 isolates of M. paratuberculosis had been cultured from patients with Crohn's disease in the USA, Australia , the Netherlands and France (Chiodini, 1989).

 

The idea for MAP-Canada was inspired by the commitment and dedication of its sister organization PARA (Paratuberculosis Awareness and Research Association Inc.) an American based organization. This grassroots movement has grown from the dedication and sheer willpower of two women with children with Crohn's disease to address the alarming rise of the bacterium "Mycobacterium avium Paratuberculosis" in the environment and the growing evidence linking this bacterium to Crohn's disease. MAP-Canada was founded to address the same issue, but on Canadian soil. One hundred thousand or more people in Canada, and over a million in the United States have been diagnosed with Crohn's. Renowned Researchers all over the world have been working with little or no funding to try and find a solution for this devastating illness.


A bacterium called Mycobacterium avium Paratuberculosis found in every day food items is connected to IBD and Crohn's disease. Before Polymerase Chain Reaction (PCR) testing, this bacterium could not be cultured. In 1984, Dr. Rodrick Chiodini cultured mycobacteria from children with Crohn's, the same bacterium found in cattle with Johne's disease. This bacterium is shed in the feces and milk of cattle with Johne's Disease.

The symptoms of this disease in both cattle and humans is very similar; severe diarrhea, excessive weight loss, debilitating abdominal pain, rectal bleeding, bowel obstruction, fistulas, and abscesses. The pasteurization process does not kill this bacterium. Thus, this mycobacterium is passed into the foodchain and sold for human consumption, as these sick cows are not removed from the herd and disposed of. Johne's disease is not on the Reportable Diseases List at the Canadian Food Inspection Agency......

Recent Article Updates

Articles
Page 2....3....4.....5

 

 

 

  What Is A Reportable Disease
 
 

To protect human and animal health, the CFIA conducts inspections and has monitoring and testing programs in place to prevent and control the spread of diseases to the livestock and poultry sectors. The CFIA carries out programs related to animal health and production to guard against the entry of foreign animal diseases and to prevent the spread of certain domestic animal diseases. Animal diseases are categorized as:

Reportable diseases
Animal owners, veterinarians and laboratories are required to immediately report the presence of an animal that is contaminated or suspected of being contaminated with one of these diseases to a CFIA district veterinarian. Control or eradication measures will be applied immediately. Federally Reportable Diseases in Canada - 2012

Immediately notifiable diseases

In general, immediately notifiable diseases are diseases exotic to Canada for which there are no control or eradication programs. Only laboratories are required to contact the CFIA regarding the suspicion or diagnosis of one of these diseases.

Annually notifiable diseases
are diseases for which Canada must submit an annual report to the World Organisation for Animal Health (OIE) indicating their presence within Canada. In general, they are diseases that are present in Canada, but are not classified as reportable or immediately notifiable.

Other Diseases Monitored by the CFIA Diseases of interest that are not currently reportable diseases or notifiable diseases.

 

Annually notifiable diseases are diseases for which Canada must submit an annual report to the World Organisation for Animal Health (OIE) indicating their presence within Canada. In general, they are diseases that are present in Canada, but are not classified as reportable or immediately notifiable. All veterinary laboratories are required to comment on Canada's report to the OIE. Annually notifiable diseases (for laboratories only) Paratuberculosis (Johne's disease) has only been added to this list. Johne's disease (Paratuberculosis) needs to be added to the Reportable diseases list, so it does not continue into our foodchain.

 

 

A Canadian Perspective on the Precautionary Approach/Principle

n the fall of 2001, the Government of Canada released a Discussion Document on the interpretation and implementation of the precautionary principle/approach. This document aims to clarify and formalise Canada's position on the precautionary principle.

In addition, is the Canadian Pasteurization process efficient enough to kill this bacterium, if it is in our milk?
  Many renowned doctors and scientists in the field of Crohn's and Johne's (yo-neez) from all over the world
say we have cause for concern. How about our water, is this bacterium in our water?

Once again, the Canadian Government has not tested our Pasteurization Process for milk to assure Canadians
that our milk is free from MAP, Mycobacterium Avium Paratuberculosis. WHY?In the United Kingdom
researcher's have found the MAP bacterium in a percentage of pasteurized milk at the retail level.

 

Join Us In Our Fight with the Canadian Government to add Johne's disease in cattle to their Reportable Diseases List, in order to eliminate this bacterium from the Canadian Food Chain.

Researchers in many parts of the world have found a link between Crohn's disease in humans and Johne's disease in cattle. This bacterium is called MAP (Mycobacterium avium Paratuberculosis). This bacterium has
been found in the breast milk of breastfeeding mothers with Crohns.  It has been found in the resected tissues of the intestinal tract of Crohn's sufferers and it has been found in milk after pasteurization, the following
websites will give you the details

The evidence contained in this site, gives the Canadian Government an obligation to study this bacterium further.Our pasteurization process has to be retested to ensure that Mycobacterium avium paratuberculosis
(Map) is eliminated from our milk.

   
   
 

What is the Crohn's Disease Initiative? A Message from Dr. Chiodini How Can I Help?

It has been almost 25-years since I first isolated M. paratuberculosis from a patient with Crohn's disease and
suggested that this organism might be the cause of some cases of Crohn's disease. Since that time, I have
seen this suggestion turn into a hostile controversy created in large part by the loss of objectivity on both sides
of the issue.

 

PROJECT UNCENSORED
MEDIA DEMOCRACY IN ACTION

April 30, 2010: Bacterium in Cow’s Milk May Cause Crohn’s Disease

Source: CLEVELAND FREE TIMES, June 16-22, 1999, Title: “The Crohn’s Connection?,” Author: Lisa Chamberlain Faculty Evaluator: Derek Girman, Ph.D. Student Researchers: Lisa Desmond & Julia O’Connor Mounting research shows that a bacterium in cow’s milk may cause Crohn’s disease, a debilitating chronic inflam-matory disease of the gastrointestinal tract.

 

WORLDNET DAILY Crohn's disease, sick cows and contaminated milk by Chris Bennett

Crohn's was unknown until the early 1900s when two very similar diseases were described: one in domestic animals called Johne's disease and one in humans named after the physician who first wrote about it, Dr. Burrill Crohn. Dr. H.A. Johne was the first to describe the disease in cattle.

 

ASM NEWS:

Microbes and Emerging Infections: the Compulsion To Become Something New Microbiologists
are advised to respect Koch's postulates while surveying for emerging and reemerging agents of
infectious disease Richard M. Krause

 

UK Essays: Crohn's Disease Inflammatory Intestine Crohn's Disease is a chronic inflammatory disease. In 1913 Dr. Kennedy Dalziel dealt with several patients with a disease called chronic intestinal enteritis. Chronic intestinal enteritis is found to be very similar to intestinal tuberculosis and was also believed to be a “new” disorder. Dr. Dalziel drew his attention to a recently described disease in cattle called pseudotuberculosis. Dalziel states, “the histological characters and naked-eye appearances are as similar as may be to those we have found in man. In many cases the absence of acid-fast bacilli would suggest a clear distinction, but the histological characters are so similar as to justify a proposition that the disease may be the same.”

 

News from the The Chronic Crohn's Campaign:

 

  Prof John Hermon Taylor In 2010 , 2011, 2012 -Vaccine Updates.

 

 

PLEASE HELP!!!!!!!

CROHN'S VACCINE APPEAL: Support the development of this treatment. Professor John Hermon-Taylor of Saint George's, University of London, is appealing for help to fund the final stages of development of a new Crohn's vaccine, which is now ready to proceed to human clinical trials

How you can help: To help raise the funds needed to develop this treatment, you can make a donation directly to St George's University of London, with the reference CROHNS A/C RLB0057 on the back. Send your donation to: Professor John Hermon-Taylor St George's University of London Cranmer Terrace LONDON, SW17 0RE St George's, University of London is a Tax Exempt Charity No: X66491. All donations received are used for research. For further information on SGUL please contact Mark Bery, SGUL Finance Director, on +44 020 8725 5024 or mbery@sgul.ac.uk. You can also help by signing the online petition to the government for funding.

 

You Tube: "Lacasastudios" New videos of John Hermon Taylor's latest Interview

Part 1 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 2 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 3 CROHN Vs M.A.P. Interview John Hermon Taylor.

Part 4 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 5 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 6 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 7 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 8 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 9 CROHN Vs M.A.P. Interview John Hermon Taylor

Part 10 CROHN Vs M.A.P. Interview John Hermon Taylor

 

You Tube:

Trailer Professor John Hermon Taylor CROHN vs M.A.P.

Part 1-CROHN M.A.P. by John Hermon Taylor

Part 2-CROHN M.A.P. by John Hermon Taylor

Part 3-CROHN M.A.P. by John Hermon Taylor

Part 4-CROHN M.A.P. by John Hermon Taylor

Part 5-CROHN M.A.P. by John Hermon Taylor

 

Youtube: Video Interview: Professor Thomas Borody Of Australia discusses M.A.P and
Crohn's: Parts 1 - 9
*******************

 

Vaccine Updates

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies para-
tuberculosis Tim J. Bull1, Sarah C. Gilbert2, Saranya Sridhar2, Richard Linedale1, Nicola Dierkes1,
Karim Sidi-Boumedine1, John Hermon-Taylor1* 1 Department of Cardiovascular Sciences-Surgery,
St George's University of London, London, United Kingdom, 2 Wellcome Trust Centre for Human Genetics,
Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom The vaccine consists of a
critically important cassette of MAP DNA in two harmless carrier viruses called Ad5 and MVA. These carriers are
already working in approved clinical trials with other modern vaccines. In the CD vaccination treatment procedure, the Ad5 is given first and the MVA boost 6 weeks later. In multiple tests in mice over two years, the vaccine has consistently proved to be effective both in treating existing MAP infection and protecting against subsequent MAP infection, without any side effects

We have come a long way and are nearly there. The vaccine will move to clinical trials and market development over the next 3 years. Over this period there is an absolute scientific requirement to develop new quantitative tests for MAP in humans, new immunological tests for MAP in humans, and tests for the specific immune responses of people to the vaccine. Together these tests will establish proof of concept that anti-MAP vaccination can make people with Crohn's disease better and it does so by depleting or eradicating the MAP infection. This final essential piece of scientific research will require £600.000

CAN YOU PLEASE HELP ? If you can, please mail your cheque direct to Dr. John Hermon-Taylor payable to “ King’s College London ” with the vaccine code JQA 1036 written on the back of cheque. The cheque can be UK £s or any major currency, Thankyou. For additionnal information please see the website The Chronic Crohn's Campaign

 

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium aviumSubspecies paratuberculo-
sis Tim J. Bull1, Sarah C. Gilbert2, Saranya Sridhar2, Richard Linedale1, Nicola Dierkes1, Karim
Sidi-Boumedine1, John Hermon-Taylor1*

1Department of Cardiovascular Sciences-Surgery,
St George’s University of London,
London, United Kingdom,
2Wellcome Trust Centre for Human Genetics,
Nuffield Department of Medicine,
University of Oxford,
Oxford, United Kingdom
:

Background.Mycobacterium aviumsubspecies paratuberculosiscauses systemic infection and chronic intestinal inflammation in many species including primates. Humans are exposed through milk and from sources of environmental contamination. Hitherto, the only vaccines available against Mycobacterium aviumsubspecies paratuberculosishave been limited to veterinary use and comprised attenuated or killed organisms.

Methods.
We developed a vaccine comprising a fusion construct designated HAV, containing components of two secreted and two cell surfaceMycobacterium aviumsubspecies paratuberculosisproteins. HAV was transformed into DNA, human Adenovirus 5 (Ad5) and Modified Vaccinia Ankara (MVA) delivery vectors. Full length expression of the predicted 95 kDa fusion protein was confirmed.

Principal Findings. Vaccination of naive and Mycobacterium aviumsubspecies paratuberculosis infected C57BL/6 mice using DNA-prime/MVA-boost or Ad5- prime/MVA-boost protocols was highly immunogenic resulting in significant IFN-c ELISPOT responses by splenocytes against recombinant vaccine antigens and a range of HAV specific peptides. This included strong recognition of a T-cell epitope GFAEINPIA located near the C-terminus of the fusion protein. Antibody responses to recombinant vaccine antigens and HAV specific peptides but not GFAEINPIA, also occurred. No immune recognition of vaccine antigens occurred in any sham vaccinatedMycobacterium aviumsubspecies paratuberculosisinfected mice. Vaccination using either protocol significantly attenuated pre-existing Mycobacterium aviumsubspecies paratuberculosis infection measured by qPCR in spleen and liver and the Ad5-prime/MVA-boost protocol also conferred some protection against subsequent challenge. No adverse effects of vaccination occurred in any of the mice.

Conclusions/Significance. A range of modern veterinary and clinical vaccines for the treatment and prevention of disease caused byMycobacterium aviumsubspecies paratuberculosisare needed. The present vaccine proved to be highly immunogenic without adverse effect in
mice and both attenuated pre-existing Mycobacterium aviumsubspeciesparatuberculosis infection and conferred protection against subsequent challenge. Further studies of the present vaccine in naturally infected animals and humans are indicated. Citation: Bull TJ, Gilbert SC, Sridhar S, Linedale R, Dierkes N, et al (2007)
A Novel Multi-Antigen Virally Vectored Vaccine againstMycobacterium avium Subspeciesparatuberculosis.
PLoS ONE 2(11): e1229. doi:10.1371/journal.pone.0001229

 

 

Youtube Video Parts 1 through 6: Mycobacteria and CD by Doctor Marcel Behr. Associate
Member, Department of Epidemiology, Biostatistics and Occupational Health, McGill
University
N.B This is an excellent video. Dr Behr explains Mycobacterium Paratuberculosis
very clearly and it is easily understood. Please watch it and give this information to anyone
else that could be interested.

 

CLOFAZAMINE

Special Access to Drugs and Health Products

Health Canada, through its Special Access Programme (SAP), allows doctors to gain access to non-marketed
drugs and medical devices that have not yet been approved for sale in Canada. Health Canada is conducting a
Comprehensive Review of the SAP and is soliciting the participation of all interested Canadians. Special Access
Request Form/Instructions for completing the Special Access Request For

 

INCREASING EVIDENCE THAT CROHN'S MAY BE AN INFECTIOUS DISEASE

Centers for Disease Control: Potential Infectious Etiologies of Crohn's Disease

 

 

 

 

 

 

Continued Page 2....3....4.....5

 

www.crohnscanada.org ~ MAP-Canada ~ MAP-Canada@crohnscanada.org

Disclaimer:
MAP-Canada does not advocate a particular cause of Crohn's disease.  Our website is intended only to present evidence.  Our readers may draw their own conclusions.  We are not medical specialists and do not offer any treatment or nutritional advice.  Our mission is not to lay blame on any individual or industry, but rather to urge the Government of Canada to address the evidence presented on this site.

Mise au Point:
MAP-Canada ne recommande aucune théorie particulière sur la cause de la maladie de Crohn.L'intente de notre site Web est simplement de présenter certaineévidence mais vous pouvez arriver à vos propres conclusions.Nous ne pouvons donner de conseils de nature médicale ou alimentaire. Notre mission ne consiste aucunement à blâmer un individuou une industrie mais
plutôt à s'assurer que le Gouvernement du Canada aborde l'évidence que nous présenton

MAP-Canada would like to extend a very sincere thank you to Yanik Chicoine at www.mirweb.com for his generosity and assistance in the hosting and the mounting of this site.

MAP-Canada aimerait remercier sincèrement Yanik Chicoine a www.mirweb.com pour sons générosité et sons assistance pour l'hébergement et la programation du site.